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Postdoctoral Fellow

Company: Texas A&M University
Location: Bryan
Posted on: October 13, 2019

Job Description:

  • An NIH-funded postdoctoral position is immediately available to investigate synaptic and circuit mechanisms of drug and alcohol addiction. Research in the lab utilizes state-of-the-science technologies, including in vivo dual-channel optogenetic (see our recent paper , ) and chemogenetic (DREADDs, see (16)32420-9/abstract) manipulation of striatal neuron activities, fiber photometry, rabies-mediated brain-wide neuronal mapping, and FosTRAP approaches in combination with behavioral procedures (e.g., operant alcohol self-administration) and slices electrophysiology. We investigate medium spiny neurons and cholinergic interneurons in the dorsomedial striatum of the basal gangalia, and how the circuitry contribute to alcohol, cocaine, and morphine abuse. For details, please visit: and -jwang188/.
  • We are seeking a highly-motivated behavioral scientist. The successful candidate will have trackable records on operant self-administration, in vivo optogenetic stimulation, and/or in vivo fiber photometry measurement. Ability to stereotaxically infuse virus in rats and/or mice is required. Experience with optogenetics, chemogenetics, FosTRAP, immunohistochemistry, or confocal imaging is a big plus. The successful applicants are expected to have a recent PhD degree in neuroscience, strong communication skills and writing ability, a record of scientific productivity, and a desire to work independently and cooperatively with a team. The candidate will have opportunity to learn slice electrophysiology.
  • Applicants with solid electrophysiology background and strong interest in using behavioral approaches are also welcome to apply. The successful electrophysiological candidate will have proven proficiency in slice electrophysiology and will study circuit-specific alterations. Ability to measure glutamatergic plasticity in acute slices using whole-cell patch-clamp recording is desired. Ability to stereotaxically infuse virus in rats and/or mice is required. Experience with optogenetics, chemogenetics, or immunohistochemistry, confocal imaging is a big plus. The successful applicants are expected to have a recent PhD degree in neuroscience, strong communication skills and writing ability, a record of scientific productivity, and a desire to work independently and cooperatively with a team.
  • The laboratory is equipped with Zeiss microscope/imaging systems, Axon MultiClamp 700B amplifiers/data acquisition systems, Sutter puller and motorized manipulators, Leica Vibratome, Optogenetic light sources, KOPF stereotaxic infusion system, Coulburn operant self-administration chambers, open field chambers, a fiber photometry system, and many optogenetic light sources , and PCR machine and workstation, Several common facilities are available within the new building that contains electrophysiological, molecular and behavioral labs.
  • Interested candidates should send Curriculum Vitae and names of three references to Dr. Jun Wang ().
  • About the institution: The Texas A&M Health Science Center is the only health science center in the Texas A&M University system that contains 11 universities. The Bryan-College Station campus of the Health Science Center are located in beautiful towns that are in a short drive to three major Texas cites -- Houston (1.5 hrs), Austin (2 hrs) and Dallas (

Keywords: Texas A&M University, Bryan , Postdoctoral Fellow, Other , Bryan, Texas

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